Organization provider

PRISMA HEALTH-UPSTATE

General Acute Care Hospital

PRISMA HEALTH-UPSTATE is an organization registered with the National Plan and Provider Enumeration System (NPPES) under NPI 1003626326, based in Simpsonville, SC. It is classified under General Acute Care Hospital.

Getting there

Here is what surrounds this office in Simpsonville, based on OpenStreetMap data collected Oct 11, 2026. Parking is available about 0.36 mi away. The nearest transit stop is 0.39 mi away, served by Grandview Dr @ Walmart. A pharmacy sits 0.49 mi from the entrance (Walgreens), which helps if you leave with a prescription.

727 SE MAIN ST STE 180, Simpsonville, SC 29681 Open in Google Maps →

Getting here and what is nearby

Transit SE Main St @ Greenville Hospital System 166 ft ~1 min
Parking 0.20 mi ~5 min
Transit Grandview Dr@ Ingles 0.30 mi ~6 min
Parking 0.32 mi ~7 min
Hotel Hampton 0.34 mi ~7 min

3934 Grandview Drive, Simpsonville 29680

Directions in Google Maps →

Restaurant Five Guys 0.34 mi ~7 min

3908 Grandview Drive, Simpsonville 29680

11:00-21:30

+1 864-881-4080

Website

Directions in Google Maps →

Restaurant Coach House Restaurant 0.35 mi ~8 min

637 Southeast Main Street, Simpsonville 29681

Website

Directions in Google Maps →

Parking 0.36 mi ~8 min
Pharmacy Connected Health Pharmacy 0.36 mi ~8 min

3097 Grandview Drive, Simpsonville 29680

Website

Directions in Google Maps →

Restaurant Outback Steakhouse 0.37 mi ~8 min

3901 Grandview Drive, Simpsonville 29680

Directions in Google Maps →

Grocery Ingles 0.37 mi ~8 min

621 Fairview Road, Simpsonville 29680

Directions in Google Maps →

Transit Grandview Dr @ Walmart 0.39 mi ~8 min
Gas station Murphy USA 0.41 mi ~9 min
Hotel Days Inn by Wyndham Simpsonville 0.41 mi ~9 min

45 Ray E Talley Court, Simpsonville 29680

+1 864-963-7701

Website

Directions in Google Maps →

Hotel Quality Inn 0.49 mi ~10 min

3755 Grandview Drive, Simpsonville 29680

Directions in Google Maps →

Pharmacy Walgreens 0.49 mi ~10 min
Grocery Walmart Supercenter 0.51 mi ~11 min

3950 Grandview Drive, Simpsonville 29680

24/7

+1 864-963-0049

Website

Directions in Google Maps →

OpenStreetMap via Overpass · ODbL 800 m radius Updated Oct 11, 2026

Distances are straight‑line estimates — walking routes may be longer. Hours and phone numbers can change; call ahead to confirm.

Credentials and Medicare

State licence

NPPES does not list a state licence number for this record. That is not unusual — organizations and some provider types are not required to file one. Verify current licensure with the relevant state board before care.

Medicare (PECOS)

This NPI does not appear in the PECOS Medicare enrolment file. Providers who do not bill Medicare — or who bill only through a group's enrolment — will not appear here. It is not a sign of any problem with the registration.

What General Acute Care Hospital covers

An acute general hospital is an institution whose primary function is to provide inpatient diagnostic and therapeutic services for a variety of medical conditions, both surgical and non-surgical, to a wide population group. The hospital treats patients in an acute phase of illness or injury, characterized by a single episode or a fairly short duration, from which the patient returns to his or her normal or previous level of activity. NUCC Health Care Provider Taxonomy, code 282N00000X
Hospitals ›General Acute Care Hospital

The taxonomy records how the provider classifies their own practice. It does not confirm which conditions they currently treat, whether they are accepting new patients, or which insurance they take — call the office for that.

Full NPPES record

An NPI-2 identifies an organization — a clinic, hospital, group practice, laboratory, or supplier. Individual clinicians working there hold their own NPI-1 numbers separately, so a bill may reference both.

NPI1003626326 valid check digit
Entity typeOrganization (NPI-2)
Enumeration dateJan 9, 2025
Last updatedJan 9, 2025
StatusActive
Practice address 727 SE MAIN ST STE 180
Simpsonville, SC 29681
(864) 455-7000
Mailing address PO BOX 402121
Atlanta, GA 30384
Other names Prisma Health Infusion Center - Hillcrest Former Legal Name
This record was updated on Jan 9, 2025, which is recent enough that the contact details are likely still accurate.

Number check

1003626326 passes the NPI check digit test The final digit 6 matches the value computed from the first nine digits, so this is a well-formed NPI.
How the check works, step by step

Every NPI carries a Luhn check digit — the same scheme used on credit cards. CMS prefixes the number with 80840 before computing it, which marks it as a US health identifier.

Digit 8 0 8 4 0 1 0 0 3 6 2 6 3 2
Doubled? — ×2 — ×2 — ×2 — ×2 — ×2 — ×2 — ×2
Value 8 0 8 8 0 2 0 0 3 3 2 3 3 4

Sum = 44 · next multiple of 10 = 50 · check digit = 6 · actual last digit = 6

A valid check digit only means the number is well-formed. It does not mean the provider is licensed, active, or in good standing — those are separate questions answered by the sections above.

Common questions

What is NPI number 1003626326?
NPI 1003626326 is the National Provider Identifier assigned to PRISMA HEALTH-UPSTATE in Simpsonville, SC. It is a 10-digit number issued by the Centers for Medicare & Medicaid Services and used on claims, referrals, and prescriptions to identify the provider.
What does General Acute Care Hospital cover?
An acute general hospital is an institution whose primary function is to provide inpatient diagnostic and therapeutic services for a variety of medical conditions, both surgical and non-surgical, to a wide population group. The hospital treats patients in an acute phase of illness or injury, characterized by a single…
How do I contact PRISMA HEALTH-UPSTATE?
The phone number on file with NPPES is (864) 455-7000, last updated Jan 9, 2025. Because NPPES is only updated when a provider files a change, call ahead to confirm the number and the current practice address before visiting.
Where do I park when visiting PRISMA HEALTH-UPSTATE?
Parking is about 0.36 mi from the office. The closest transit stop is 0.39 mi away, on Grandview Dr @ Walmart. Distances are straight-line estimates from OpenStreetMap, so walking routes may be slightly longer.
Is NPI 1003626326 a valid number?
Yes. 1003626326 passes the Luhn check digit validation that CMS uses for NPI numbers, and it resolves to an active record in the registry.
How to use this page. Everything here comes from public federal records. Tips Health does not verify quality of care, confirm that a licence is currently active, or check malpractice history, and accepts no fees for placement. A listing is not a recommendation. Verify independently before seeking care.